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Modified Polyadenylation-Based RT-qPCR Increases Selectivity of Amplification of 3′-MicroRNA Isoforms

MicroRNA (miRNA) detection by reverse transcription (RT) quantitative real-time PCR (RT-qPCR) is the most popular method currently used to measure miRNA expression. Although the majority of miRNA families are constituted of several 3′-end length variants (“isomiRs”), little attention has been paid t...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Nejad, Charlotte, Pépin, Geneviève, Behlke, Mark A., Gantier, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787544/
https://ncbi.nlm.nih.gov/pubmed/29416548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00011
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