Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling

Inflammatory bowel disease (IBD) increases the risk of colorectal cancer, known as colitis-associated cancer (CAC). It is still unclear what driver mutations are caused by chronic inflammation and lead to CAC development. To get insight into this issue, we investigated somatic alterations in CAC. We...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fujita, Masashi, Matsubara, Nagahide, Matsuda, Ikuo, Maejima, Kazuhiro, Oosawa, Ayako, Yamano, Tomoki, Fujimoto, Akihiro, Furuta, Mayuko, Nakano, Kaoru, Oku-Sasaki, Aya, Tanaka, Hiroko, Shiraishi, Yuichi, Mateos, Raúl Nicolás, Nakai, Kenta, Miyano, Satoru, Tomita, Naohiro, Hirota, Seiichi, Ikeuchi, Hiroki, Nakagawa, Hidewaki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787528/
https://ncbi.nlm.nih.gov/pubmed/29416670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22867
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