In vitro and in vivo anti-leukemic effects of cladoloside C(2) are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c-Jun NH(2)-terminal kinase/caspase-8

We previously demonstrated that the quinovose-containing hexaoside stichoposide C (STC) is a more potent anti-leukemic agent than the glucose-containing stichoposide D (STD), and that these substances have different molecular mechanisms of action. In the present study, we investigated the novel mari...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yun, Seong-Hoon, Sim, Eun-Hye, Han, Sang-Heum, Kim, Tae-Rang, Ju, Mi-Ha, Han, Jin-Yeong, Jeong, Jin-Sook, Kim, Sung-Hyun, Silchenko, Alexandra S., Stonik, Valentin A., Park, Joo-In
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787484/
https://ncbi.nlm.nih.gov/pubmed/29416631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23069
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