By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, Stichoposide D inhibits growth of leukemia xenografts

Stichoposide D (STD) is a marine triterpene glycoside isolated from sea cucumbers. We examined the molecular mechanisms underlying the antitumor activity of STD in human leukemia cells. The role of Fas (CD95), ceramide synthase 6 (CerS6) and p38 kinase during STD-induced apoptosis was examined in hu...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Yun, Seong-Hoon, Park, Eun-Seon, Shin, Sung-Won, Ju, Mi-Ha, Han, Jin-Yeong, Jeong, Jin-Sook, Kim, Sung-Hyun, Stonik, Valentin A., Kwak, Jong-Young, Park, Joo-In
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695011/
https://ncbi.nlm.nih.gov/pubmed/26318294
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki