Defining murine organogenesis at single cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation

During gastrulation, cell types from all three germ layers are specified and the basic body plan is established1. However, molecular analysis of this key developmental stage has been hampered by limited cell numbers and a paucity of markers. Single cell RNA sequencing circumvents these problems, but...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Ibarra-Soria, Ximena, Jawaid, Wajid, Pijuan-Sala, Blanca, Ladopoulos, Vasileios, Scialdone, Antonio, Jörg, David J, Tyser, Richard, Calero-Nieto, Fernando J, Mulas, Carla, Nichols, Jennifer, Vallier, Ludovic, Srinivas, Shankar, Simons, Benjamin D, Göttgens, Berthold, Marioni, John C
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787369/
https://ncbi.nlm.nih.gov/pubmed/29311656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-017-0013-z
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