Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism

BACKGROUND: Our aim was to evaluate lipid trafficking and inflammatory response of macrophages exposed to lipoproteins from subjects with moderate to severe chronic kidney disease (CKD), and to investigate the potential benefits of activating cellular cholesterol transporters via liver X receptor (L...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Kaseda, Ryohei, Tsuchida, Yohei, Yang, Hai-Chun, Yancey, Patricia G., Zhong, Jianyong, Tao, Huan, Bian, Aihua, Fogo, Agnes B., Linton, Mac Rae F., Fazio, Sergio, Ikizler, Talat Alp, Kon, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787279/
https://ncbi.nlm.nih.gov/pubmed/29374468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-018-0814-8
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