Macrophage Polarization by Angiotensin II-type 1 Receptor Aggravates Renal Injury-acceleration of Atherosclerosis

BACKGROUND: Angiotensin II (AII) is a major determinant of atherosclerosis. Although macrophages are the most abundant cells in atherosclerotic plaques and express AII type 1 receptor (AT1), the pathophysiologic role of macrophage AT1 in atherogenesis remains uncertain. We examined the contribution...

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Main Authors: Yamamoto, Suguru, Yancey, Patricia G., Zuo, Yiqin, Ma, Li-Jun, Kaseda, Ryohei, Fogo, Agnes B., Ichikawa, Iekuni, Linton, MacRae F., Fazio, Sergio, Kon, Valentina
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227118/
https://ncbi.nlm.nih.gov/pubmed/21979434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.237198
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