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Flow Cytometric Clinical Immunomonitoring Using Peptide–MHC Class II Tetramers: Optimization of Methods and Protocol Development

With the advent of novel strategies to induce tolerance in autoimmune and autoimmune-like conditions, clinical trials of antigen-specific tolerizing immunotherapy have become a reality. Besides safety, it will be essential to gather mechanistic data on responding CD4(+) T cells to assess the effects...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J., Thomas, Ranjeny
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786526/
https://ncbi.nlm.nih.gov/pubmed/29403492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00008
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