Sensitive liquid chromatography/tandem mass spectrometry method for the determination of two novel highly lipophilic anti-cancer drug candidates in rat plasma and tissues

A simple and sensitive liquid chromatography/electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS) method was developed and validated for determination of two highly lipophilic anti-cancer drug candidates, LG1980, and GH501, in rat plasma and tissues (liver, kidney and femur bones). LG1980...

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Dettagli Bibliografici
Pubblicato in:Biomed Chromatogr
Autori principali: Hooshfar, Shirin, Linzey, Michael R., Wu, Daqing, Gera, Lajos, Mamouni, Kenza, Li, Xin, Chen, Yanhua, Yang, Yang, Olorunyolemi, Oluwasegun, Bartlett, Michael G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786476/
https://ncbi.nlm.nih.gov/pubmed/28801923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.4064
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