The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection

PURPOSE: To characterize the mediators of 5-HT(2A) serotonin receptor–driven retinal neuroprotection. METHODS: Albino mice were treated intraperitoneally with saline or sarpogrelate, a 5-HT(2A) antagonist, immediately before light exposure (LE). Following LE, retinas were harvested for a high-throug...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Ku, Cristy A., Ryals, Renee C., Jiang, Dan, Coyner, Aaron S., Weller, Kyle K., Sinha, Wrik, Robb, Bryan M., Yang, Paul, Pennesi, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786286/
https://ncbi.nlm.nih.gov/pubmed/29368005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23159
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