Sarpogrelate, a 5-HT(2A) Receptor Antagonist, Protects the Retina From Light-Induced Retinopathy

PURPOSE: To determine if sarpogrelate, a selective 5-HT(2A) receptor antagonist, is protective against light-induced retinopathy in BALB/c mice. METHODS: BALB/c mice were dosed intraperitoneally with 5, 15, 30, 40, or 50 mg/kg sarpogrelate 48, 24, and 0 hours prior to bright light exposure (10,000 l...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Tullis, Brandon E., Ryals, Renee C., Coyner, Aaron S., Gale, Michael J., Nicholson, Alex, Ku, Cristy, Regis, Dain, Sinha, Wrik, Datta, Shreya, Wen, Yuquan, Yang, Paul, Pennesi, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Visual Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515947/
https://ncbi.nlm.nih.gov/pubmed/26200496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16378
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