C-reactive protein and pentraxin-3 binding of factor H-like protein 1 differs from complement factor H: implications for retinal inflammation

Retinal inflammation plays a key role in the progression of age-related macular degeneration (AMD), a condition that leads to loss of central vision. The deposition of the acute phase pentraxin C-reactive protein (CRP) in the macula activates the complement system, thereby contributing to dysregulat...

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Publicado en:Sci Rep
Main Authors: Swinkels, Maurice, Zhang, Justine H., Tilakaratna, Viranga, Black, Graeme, Perveen, Rahat, McHarg, Selina, Inforzato, Antonio, Day, Anthony J., Clark, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786067/
https://ncbi.nlm.nih.gov/pubmed/29374201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18395-7
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