Factor H–Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation

The physiological roles of the factor H (FH)-related proteins are controversial and poorly understood. Based on genetic studies, FH-related protein 5 (CFHR5) is implicated in glomerular diseases, such as atypical hemolytic uremic syndrome, dense deposit disease, and CFHR5 nephropathy. CFHR5 was also...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Csincsi, Ádám I., Kopp, Anne, Zöldi, Miklós, Bánlaki, Zsófia, Uzonyi, Barbara, Hebecker, Mario, Caesar, Joseph J. E., Pickering, Matthew C., Daigo, Kenji, Hamakubo, Takao, Lea, Susan M., Goicoechea de Jorge, Elena, Józsi, Mihály
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Molecular and Structural Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416742/
https://ncbi.nlm.nih.gov/pubmed/25855355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403121
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