Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

Epigenetic mechanisms and transcription factor networks essential for differentiation of cardiac myocytes have been uncovered. However, reshaping of the epigenome of these terminally differentiated cells during fetal development, postnatal maturation, and in disease remains unknown. Here, we investi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gilsbach, Ralf, Schwaderer, Martin, Preissl, Sebastian, Grüning, Björn A., Kranzhöfer, David, Schneider, Pedro, Nührenberg, Thomas G., Mulero-Navarro, Sonia, Weichenhan, Dieter, Braun, Christian, Dreßen, Martina, Jacobs, Adam R., Lahm, Harald, Doenst, Torsten, Backofen, Rolf, Krane, Markus, Gelb, Bruce D., Hein, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786002/
https://ncbi.nlm.nih.gov/pubmed/29374152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02762-z
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