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Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression
Fractional killing is the main cause of tumour resistance to chemotherapy. This phenomenon is observed even in genetically identical cancer cells in homogeneous microenvironments. To understand this variable resistance, here we investigate the individual responses to TRAIL in a clonal population of...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785974/ https://ncbi.nlm.nih.gov/pubmed/29374163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02787-4 |
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