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An Alanine-to-Valine Substitution in the Residue 175 of Zika Virus NS2A Protein Affects Viral RNA Synthesis and Attenuates the Virus In Vivo

The recent outbreaks of Zika virus (ZIKV), its association with Guillain–Barré syndrome and fetal abnormalities, and the lack of approved vaccines and antivirals, highlight the importance of developing countermeasures to combat ZIKV disease. In this respect, infectious clones constitute excellent to...

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Bibliografiska uppgifter
I publikationen:Viruses
Huvudupphovsmän: Márquez-Jurado, Silvia, Nogales, Aitor, Ávila-Pérez, Ginés, Iborra, Francisco J., Martínez-Sobrido, Luis, Almazán, Fernando
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212934/
https://ncbi.nlm.nih.gov/pubmed/30301244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10100547
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