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Reducing persistent polyomavirus infection increases functionality of virus-specific memory CD8 T cells

Mouse polyomavirus (MuPyV) causes a smoldering persistent infection in immunocompetent mice. To lower MuPyV infection in acutely and persistently infected mice, and study the impact of a temporal reduction in viral loads on the memory CD8 T cell response, we created a recombinant MuPyV in which a lo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Virology
Prif Awduron: Qin, Qingsong, Lauver, Matthew, Maru, Saumya, Lin, Eugene, Lukacher, Aron E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785946/
https://ncbi.nlm.nih.gov/pubmed/28063344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.12.028
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