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TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection

Establishing functional tissue-resident memory (T(RM)) cells at sites of infection is a newfound objective of T cell vaccine design. To directly assess the impact of antigen stimulation strength on memory CD8 T cell formation and function during a persistent viral infection, we created a library of...

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發表在:PLoS Pathog
Main Authors: Maru, Saumya, Jin, Ge, Schell, Todd D., Lukacher, Aron E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406018/
https://ncbi.nlm.nih.gov/pubmed/28410427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006318
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