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TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection
Establishing functional tissue-resident memory (T(RM)) cells at sites of infection is a newfound objective of T cell vaccine design. To directly assess the impact of antigen stimulation strength on memory CD8 T cell formation and function during a persistent viral infection, we created a library of...
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Publicado no: | PLoS Pathog |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406018/ https://ncbi.nlm.nih.gov/pubmed/28410427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006318 |
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