Evidence for genetic overlap between schizophrenia and age at first birth in women

IMPORTANCE: A recent published study of national data showed increased risk of schizophrenia (SCZ) in offspring associated with both early and delayed parental age, consistent with a U-shaped relationship. However, it remains unclear if the risk to the child is due to psychosocial factors associated...

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Pubblicato in:JAMA Psychiatry
Autori principali: Mehta, Divya, Tropf, Felix C, Gratten, Jacob, Bakshi, Andrew, Zhu, Zhihong, Bacanu, Silviu-Alin, Hemani, Gibran, Magnusson, Patrik KE, Barban, Nicola, Esko, Tõnu, Metspalu, Andres, Snieder, Harold, Mowry, Bryan J, Kendler, Kenneth S, Yang, Jian, Visscher, Peter M, McGrath, John J, Mills, Melinda C, Wray, Naomi R, Hong Lee, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785705/
https://ncbi.nlm.nih.gov/pubmed/27007234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2016.0129
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