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Determination of flutamide and two major metabolites using HPLC–DAD and HPTLC methods
Flutamide is a potential antineoplastic drug classified as an anti-androgen. It is a therapy for men with advanced prostate cancer, administered orally after which it undergoes extensively first pass metabolism in the liver with the production of several metabolites. These metabolites are predominan...
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| Publicado no: | Chem Cent J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785457/ https://ncbi.nlm.nih.gov/pubmed/29372342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0372-y |
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