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Growth Differentiation Factor 6 (GDF6) promotes vascular stability by restraining VEGF signaling

OBJECTIVE: The assembly of a functional vascular system requires a coordinated and dynamic transition from activation to maturation. High VEGF activity promotes activation, including junction destabilization and cell motility. Maturation involves junctional stabilization and formation of a functiona...

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Bibliographische Detailangaben
Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Krispin, Shlomo, Stratman, Amber N., Melick, Chase H., Stan, Radu V., Malinverno, Matteo, Gleklen, Jamie, Castranova, Daniel, Dejana, Elisabetta, Weinstein, Brant M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785447/
https://ncbi.nlm.nih.gov/pubmed/29284606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309571
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