Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance

The molecular mechanism by which cancer-associated fibroblasts (CAFs) confer chemoresistance in ovarian cancer is poorly understood. The purpose of the present study was to evaluate the roles of CAFs in modulating tumor vasculature, chemoresistance, and disease progression. Here, we found that CAFs...

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: Leung, Cecilia S., Yeung, Tsz-Lun, Yip, Kay-Pong, Wong, Kwong-Kwok, Ho, Samuel Y., Mangala, Lingegowda S., Sood, Anil K., Lopez-Berestein, Gabriel, Sheng, Jianting, Wong, Stephen T.C., Birrer, Michael J., Mok, Samuel C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785271/
https://ncbi.nlm.nih.gov/pubmed/29251630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95200
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