PBX transcription factors drive pulmonary vascular adaptation to birth

A critical event in the adaptation to extrauterine life is relaxation of the pulmonary vasculature at birth, allowing for a rapid increase in pulmonary blood flow that is essential for efficient gas exchange. Failure of this transition leads to pulmonary hypertension (PH), a major cause of newborn m...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: McCulley, David J., Wienhold, Mark D., Hines, Elizabeth A., Hacker, Timothy A., Rogers, Allison, Pewowaruk, Ryan J., Zewdu, Rediet, Chesler, Naomi C., Selleri, Licia, Sun, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785269/
https://ncbi.nlm.nih.gov/pubmed/29251627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93395
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