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BAD and K(ATP) channels regulate neuron excitability and epileptiform activity
Brain metabolism can profoundly influence neuronal excitability. Mice with genetic deletion or alteration of Bad (BCL-2 agonist of cell death) exhibit altered brain-cell fuel metabolism, accompanied by resistance to acutely induced epileptic seizures; this seizure protection is mediated by ATP-sensi...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785210/ https://ncbi.nlm.nih.gov/pubmed/29368690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32721 |
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