BAD-Dependent Regulation of Fuel Metabolism and K(ATP) Channel Activity Confers Resistance to Epileptic Seizures

Neuronal excitation can be substantially modulated by alterations in metabolism, as evident from the anticonvulsant effect of diets that reduce glucose utilization and promote ketone body metabolism. We provide genetic evidence that BAD, a protein with dual functions in apoptosis and glucose metabol...

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Detalhes bibliográficos
Main Authors: Giménez-Cassina, Alfredo, Martínez-François, Juan Ramón, Fisher, Jill K., Szlyk, Benjamin, Polak, Klaudia, Wiwczar, Jessica, Tanner, Geoffrey R., Lutas, Andrew, Yellen, Gary, Danial, Nika N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361694/
https://ncbi.nlm.nih.gov/pubmed/22632729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.03.032
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