BAD-Dependent Regulation of Fuel Metabolism and K(ATP) Channel Activity Confers Resistance to Epileptic Seizures

Neuronal excitation can be substantially modulated by alterations in metabolism, as evident from the anticonvulsant effect of diets that reduce glucose utilization and promote ketone body metabolism. We provide genetic evidence that BAD, a protein with dual functions in apoptosis and glucose metabol...

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Bibliografiske detaljer
Main Authors: Giménez-Cassina, Alfredo, Martínez-François, Juan Ramón, Fisher, Jill K., Szlyk, Benjamin, Polak, Klaudia, Wiwczar, Jessica, Tanner, Geoffrey R., Lutas, Andrew, Yellen, Gary, Danial, Nika N.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361694/
https://ncbi.nlm.nih.gov/pubmed/22632729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.03.032
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