Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative trait loci (QTLs) modulating CCT in the mouse with...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: King, Rebecca, Struebing, Felix L., Li, Ying, Wang, Jiaxing, Koch, Allison Ashley, Cooke Bailey, Jessica N., Gharahkhani, Puya, MacGregor, Stuart, Allingham, R. Rand, Hauser, Michael A., Wiggs, Janey L., Geisert, Eldon E.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784889/
https://ncbi.nlm.nih.gov/pubmed/29370175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007145
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