Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative trait loci (QTLs) modulating CCT in the mouse with...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: King, Rebecca, Struebing, Felix L., Li, Ying, Wang, Jiaxing, Koch, Allison Ashley, Cooke Bailey, Jessica N., Gharahkhani, Puya, MacGregor, Stuart, Allingham, R. Rand, Hauser, Michael A., Wiggs, Janey L., Geisert, Eldon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784889/
https://ncbi.nlm.nih.gov/pubmed/29370175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007145
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