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Bispecific antibodies: design, therapy, perspectives

Antibodies (Abs) containing two different antigen-binding sites in one molecule are called bispecific. Bispecific Abs (BsAbs) were first described in the 1960s, the first monoclonal BsAbs were generated in the 1980s by hybridoma technology, and the first article describing the therapeutic use of BsA...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Sedykh, Sergey E, Prinz, Victor V, Buneva, Valentina N, Nevinsky, Georgy A
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784585/
https://ncbi.nlm.nih.gov/pubmed/29403265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S151282
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