ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems

BACKGROUND: The development of particokinetic models describing the delivery of insoluble or poorly soluble nanoparticles to cells in liquid cell culture systems has improved the basis for dose-response analysis, hazard ranking from high-throughput systems, and now allows for translation of exposure...

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Библиографические подробности
Опубликовано в: :Part Fibre Toxicol
Главные авторы: Thomas, Dennis G., Smith, Jordan N., Thrall, Brian D., Baer, Donald R., Jolley, Hadley, Munusamy, Prabhakaran, Kodali, Vamsi, Demokritou, Philip, Cohen, Joel, Teeguarden, Justin G.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784555/
https://ncbi.nlm.nih.gov/pubmed/29368623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-018-0243-7
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