ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems

BACKGROUND: The development of particokinetic models describing the delivery of insoluble or poorly soluble nanoparticles to cells in liquid cell culture systems has improved the basis for dose-response analysis, hazard ranking from high-throughput systems, and now allows for translation of exposure...

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Vydáno v:Part Fibre Toxicol
Hlavní autoři: Thomas, Dennis G., Smith, Jordan N., Thrall, Brian D., Baer, Donald R., Jolley, Hadley, Munusamy, Prabhakaran, Kodali, Vamsi, Demokritou, Philip, Cohen, Joel, Teeguarden, Justin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784555/
https://ncbi.nlm.nih.gov/pubmed/29368623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-018-0243-7
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