ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

BACKGROUND: The difficulty of directly measuring cellular dose is a significant obstacle to application of target tissue dosimetry for nanoparticle and microparticle toxicity assessment, particularly for in vitro systems. As a consequence, the target tissue paradigm for dosimetry and hazard assessme...

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Hauptverfasser: Hinderliter, Paul M, Minard, Kevin R, Orr, Galya, Chrisler, William B, Thrall, Brian D, Pounds, Joel G, Teeguarden, Justin G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012653/
https://ncbi.nlm.nih.gov/pubmed/21118529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-7-36
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