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Role of Deficient DNA Mismatch Repair Status in Patients With Stage III Colon Cancer Treated With FOLFOX Adjuvant Chemotherapy: A Pooled Analysis From 2 Randomized Clinical Trials

IMPORTANCE: The prognostic impact of DNA mismatch repair (MMR) status in stage III colon cancer patients receiving FOLFOX (folinic acid, fluorouracil, and oxaliplatin) adjuvant chemotherapy remains controversial. OBJECTIVE: To determine the association of MMR status with disease-free survival (DFS)...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Zaanan, Aziz, Shi, Qian, Taieb, Julien, Alberts, Steven R., Meyers, Jeffrey P., Smyrk, Thomas C., Julie, Catherine, Zawadi, Ayman, Tabernero, Josep, Mini, Enrico, Goldberg, Richard M., Folprecht, Gunnar, Van Laethem, Jean Luc, Le Malicot, Karine, Sargent, Daniel J., Laurent-Puig, Pierre, Sinicrope, Frank A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784452/
https://ncbi.nlm.nih.gov/pubmed/28983557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.2899
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