Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence

Candida albicans is an opportunistic fungal pathogen responsible for superficial and life-threatening infections in humans. During mucosal infection, C. albicans undergoes a morphological transition from yeast to invasive filamentous hyphae that secrete candidalysin, a 31-amino-acid peptide toxin re...

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Vydáno v:mBio
Hlavní autoři: Richardson, Jonathan P., Mogavero, Selene, Moyes, David L., Blagojevic, Mariana, Krüger, Thomas, Verma, Akash H., Coleman, Bianca M., De La Cruz Diaz, Jacinto, Schulz, Daniela, Ponde, Nicole O., Carrano, Giulia, Kniemeyer, Olaf, Wilson, Duncan, Bader, Oliver, Enoiu, Simona I., Ho, Jemima, Kichik, Nessim, Gaffen, Sarah L., Hube, Bernhard, Naglik, Julian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784256/
https://ncbi.nlm.nih.gov/pubmed/29362237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02178-17
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