Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1)

Targeting drugs to endothelial cells has shown the ability to improve outcomes in animal models of inflammatory, ischemic and thrombotic diseases. Previous studies have revealed that certain pairs of ligands (antibodies and antibody fragments) specific for adjacent, but distinct, epitopes on PECAM-1...

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Publicat a:Sci Rep
Autors principals: Kiseleva, Raisa Yu., Greineder, C. F., Villa, C. H., Marcos-Contreras, O. A., Hood, E. D., Shuvaev, V. V., DeLisser, H. M., Muzykantov, V. R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784113/
https://ncbi.nlm.nih.gov/pubmed/29367646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20027-7
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