Intravitreal injection of aflibercept, an anti-VEGF antagonist, down-regulates plasma von Willebrand factor in patients with age-related macular degeneration

We investigated the association between von Willebrand factor (VWF) and exudative age-related macular degeneration (AMD) in 114 Japanese patients. Intravitreal injection of vascular endothelial growth factor (VEGF) inhibitor is the most effective therapy for AMD. Therefore, we analyzed changes of VW...

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Vydáno v:Sci Rep
Hlavní autoři: Yamashita, Mariko, Matsumoto, Masanori, Hayakawa, Masaki, Sakai, Kazuya, Fujimura, Yoshihiro, Ogata, Nahoko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784081/
https://ncbi.nlm.nih.gov/pubmed/29367644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19473-0
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