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Common Pathophysiology in Multiple Mouse Models of Pitt–Hopkins Syndrome

Mutations or deletions of the transcription factor TCF4 are linked to Pitt–Hopkins syndrome (PTHS) and schizophrenia, suggesting that the precise pathogenic mutations dictate cellular, synaptic, and behavioral consequences. Here, we generated two novel mouse models of PTHS, one that mimics the most...

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書誌詳細
出版年:J Neurosci
主要な著者: Thaxton, Courtney, Kloth, Alexander D., Clark, Ellen P., Moy, Sheryl S., Chitwood, Raymond A., Philpot, Benjamin D.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783968/
https://ncbi.nlm.nih.gov/pubmed/29222403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1305-17.2017
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