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Shielding and activation of a viral membrane fusion protein

Entry of enveloped viruses relies on insertion of hydrophobic residues of the viral fusion protein into the host cell membrane. However, the intermediate conformations during fusion remain unknown. Here, we address the fusion mechanism of Rift Valley fever virus. We determine the crystal structure o...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Halldorsson, Steinar, Li, Sai, Li, Mengqiu, Harlos, Karl, Bowden, Thomas A., Huiskonen, Juha T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783950/
https://ncbi.nlm.nih.gov/pubmed/29367607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02789-2
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