A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination

Erroneous DNA repair by heterologous recombination (Ht-REC) is a potential threat to genome stability, but evidence supporting its prevalence is lacking. Here we demonstrate that recombination is possible between heterologous sequences and that it is a source of chromosomal alterations in mitotic an...

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Bibliographic Details
Published in:Mol Cell
Main Authors: León-Ortiz, Ana María, Panier, Stephanie, Sarek, Grzegorz, Vannier, Jean-Baptiste, Patel, Harshil, Campbell, Peter J., Boulton, Simon J.
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783719/
https://ncbi.nlm.nih.gov/pubmed/29351848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.12.014
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