Bone metastasis of prostate cancer can be therapeutically targeted at the TBX2-WNT signaling axis

Identification of factors that mediate visceral and bone metastatic spread and subsequent bone remodeling events is highly relevant to successful therapeutic intervention in advanced human prostate cancer (PCa). TBX2, a T-box family transcription factor that negatively regulates cell cycle inhibitor...

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Pubblicato in:Cancer Res
Autori principali: Nandana, Srinivas, Tripathi, Manisha, Duan, Peng, Chu, Chia-Yi, Mishra, Rajeev, Liu, Chunyan, Jin, Renjie, Yamashita, Hironobu, Zayzafoon, Majd, Bhowmick, Neil A., Zhau, Haiyen E., Matusik, Robert J., Chung, Leland W.K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783646/
https://ncbi.nlm.nih.gov/pubmed/28108510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0497
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