Modulation of cabozantinib efficacy by the prostate tumor microenvironment

The tumor microenvironment (TME) is increasingly recognized as the arbiter of metastatic progression and drug resistance in advanced prostate cancer (PCa). Cabozantinib is a potent tyrosine kinase inhibitor (TKI) with reported biological activity in the PCa epithelia, but failed to provide an overal...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tripathi, Manisha, Nandana, Srinivas, Billet, Sandrine, Cavassani, Karen A., Mishra, Rajeev, Chung, Leland W.K., Posadas, Edwin M., Bhowmick, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675680/
https://ncbi.nlm.nih.gov/pubmed/29152128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21248
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