EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway

Although the introduction of tyrosine kinase inhibitors greatly improved the survival of patients with chronic myeloid leukemia (CML), drug resistance remains a problem. Thus, mechanism-based novel therapeutic targets warrant exploration. Recently, epidermal growth factor receptor kinase substrate 8...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncol Rep
Prif Awduron: Huang, Rui, Liu, Huimin, Chen, Yiran, He, Yanjie, Kang, Qian, Tu, Sanfang, He, Yingzhi, Zhou, Xuan, Wang, Lei, Yang, Jilong, Wu, Anqin, Li, Yuhua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2018
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783592/
https://ncbi.nlm.nih.gov/pubmed/29192326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.6102
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