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CRISPR/Cas9 targeting of the androgen receptor suppresses the growth of LNCaP human prostate cancer cells

Androgens have been recognized to be primary causative agents of prostate cancer. Following binding to the androgen receptor (AR), androgens serve important roles in the carcinogenesis of prostate cancers. ARs serve an important role during all stages of prostate cancer, and inhibiting their functio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: Wei, Chaogang, Wang, Fengjiao, Liu, Wei, Zhao, Wenlu, Yang, Yi, Li, Kai, Xiao, Li, Shen, Junkang
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783506/
https://ncbi.nlm.nih.gov/pubmed/29257308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.8257
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