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PKC-Mediated Secretion of Death Factors in LNCaP Prostate Cancer Cells Is Regulated by Androgens
Activation of PKCδ in androgen-dependent LNCaP prostate cancer cells leads to apoptosis via the activation of p38 MAPK and JNK cascades. We have recently shown that treatment of LNCaP cells with phorbol 12-myristate 13-acetate (PMA) leads to a PKCδ-mediated autocrine release of death factors, includ...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113613/ https://ncbi.nlm.nih.gov/pubmed/18756441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20476 |
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