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Novel anti-cancer drug COTI-2 synergizes with therapeutic agents and does not induce resistance or exhibit cross-resistance in human cancer cell lines

Emerging drug-resistance and drug-associated toxicities are two major factors limiting successful cancer therapy. Combinations of chemotherapeutic drugs have been used in the clinic to improve patient outcome. However, cancer cells can acquire resistance to drugs, alone or in combination. Resistant...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Maleki Vareki, Saman, Salim, Kowthar Y., Danter, Wayne R., Koropatnick, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783418/
https://ncbi.nlm.nih.gov/pubmed/29364966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191766
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