Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease

INTRODUCTION: Overt fibrostenotic disease is a relative contraindication for anti-TNF therapy in Crohn’s disease. We hypothesized that subclinical fibrosis may also contribute to an incomplete response to anti-TNF therapy before the onset of symptomatic stenosis. METHODS: In a previous trial, patien...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: de Bruyn, Jessica R., Becker, Marte A., Steenkamer, Jessica, Wildenberg, Manon E., Meijer, Sybren L., Buskens, Christianne J., Bemelman, Willem A., Löwenberg, Mark, Ponsioen, Cyriel Y., van den Brink, Gijs R., D’Haens, Geert R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783363/
https://ncbi.nlm.nih.gov/pubmed/29364909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190999
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