Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease

INTRODUCTION: Overt fibrostenotic disease is a relative contraindication for anti-TNF therapy in Crohn’s disease. We hypothesized that subclinical fibrosis may also contribute to an incomplete response to anti-TNF therapy before the onset of symptomatic stenosis. METHODS: In a previous trial, patien...

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發表在:PLoS One
Main Authors: de Bruyn, Jessica R., Becker, Marte A., Steenkamer, Jessica, Wildenberg, Manon E., Meijer, Sybren L., Buskens, Christianne J., Bemelman, Willem A., Löwenberg, Mark, Ponsioen, Cyriel Y., van den Brink, Gijs R., D’Haens, Geert R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783363/
https://ncbi.nlm.nih.gov/pubmed/29364909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190999
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