Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

Chloride ions play an important role in controlling excitability of principal neurons in the central nervous system. When neurotransmitter GABA is released from inhibitory interneurons, activated GABA type A (GABA(A)) receptors on principal neurons become permeable to chloride. Typically, chloride f...

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Bibliografske podrobnosti
izdano v:eNeuro
Main Authors: Sørensen, Andreas T., Ledri, Marco, Melis, Miriam, Nikitidou Ledri, Litsa, Andersson, My, Kokaia, Merab
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2018
Teme:
New Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783240/
https://ncbi.nlm.nih.gov/pubmed/29379872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0172-17.2017
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