Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

Chloride ions play an important role in controlling excitability of principal neurons in the central nervous system. When neurotransmitter GABA is released from inhibitory interneurons, activated GABA type A (GABA(A)) receptors on principal neurons become permeable to chloride. Typically, chloride f...

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Dettagli Bibliografici
Pubblicato in:eNeuro
Autori principali: Sørensen, Andreas T., Ledri, Marco, Melis, Miriam, Nikitidou Ledri, Litsa, Andersson, My, Kokaia, Merab
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
Soggetti:
New Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783240/
https://ncbi.nlm.nih.gov/pubmed/29379872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0172-17.2017
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