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P08.67 Inhibition of MutT homolog 1 (MTH1) in glioblastoma multiforme results in impaired cell migration and tumor growth
INTRODUCTION: MutT homolog1 (MTH1) is required for survival of cancer cells. These have irregular redox formation resulting in the production of reactive oxygen species which damage the deoxynucleoside triphosphate pool and subsequent the DNA. MTH1 plays a crucial role by inhibiting the incorporatio...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782695/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.200 |
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