P08.48 Combined alterations in MAPK pathway genes, CDKN2A/B and ATRX characterize anaplastic pilocytic astrocytoma

Tumors with histological features of pilocytic astrocytoma but with increased mitotic activity and additional high grade features (i.e. microvascular proliferation, necrosis) have been designated anaplastic pilocytic astrocytomas (APA). Patients with such tumors are thought to have an unfavorable cl...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Kratz, A., Sahm, F., Schrimpf, D., Jones, D. T., Reuss, D. E., Schittenhelm, J., Gramatzki, D., Felsberg, J., von Deimling, A., Capper, D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
P08 Glioblastom and Anaplastic gliomas
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782676/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.181
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