P08.48 Combined alterations in MAPK pathway genes, CDKN2A/B and ATRX characterize anaplastic pilocytic astrocytoma

Tumors with histological features of pilocytic astrocytoma but with increased mitotic activity and additional high grade features (i.e. microvascular proliferation, necrosis) have been designated anaplastic pilocytic astrocytomas (APA). Patients with such tumors are thought to have an unfavorable cl...

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Vydáno v:Neuro Oncol
Hlavní autoři: Kratz, A., Sahm, F., Schrimpf, D., Jones, D. T., Reuss, D. E., Schittenhelm, J., Gramatzki, D., Felsberg, J., von Deimling, A., Capper, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
P08 Glioblastom and Anaplastic gliomas
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782676/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.181
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