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P08.48 Combined alterations in MAPK pathway genes, CDKN2A/B and ATRX characterize anaplastic pilocytic astrocytoma

Tumors with histological features of pilocytic astrocytoma but with increased mitotic activity and additional high grade features (i.e. microvascular proliferation, necrosis) have been designated anaplastic pilocytic astrocytomas (APA). Patients with such tumors are thought to have an unfavorable cl...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kratz, A., Sahm, F., Schrimpf, D., Jones, D. T., Reuss, D. E., Schittenhelm, J., Gramatzki, D., Felsberg, J., von Deimling, A., Capper, D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782676/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.181
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