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P06.02 Transcriptional profiling to identify determinants associated with response to ABT-414 in patients with glioblastoma
BACKGROUND: Aberrant epidermal growth factor receptor (EGFR) expression, such as amplification, overexpression or EGFRvIII mutation, is common in glioblastoma (GBM). ABT-414 is an EGFR-targeted antibody conjugated to a toxic antimicrotubule agent, monomethyl auristatin F. In an ongoing phase I study...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782591/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.093 |
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