REST represses miR-124 and miR-203 to regulate distinct oncogenic properties of glioblastoma stem cells

BACKGROUND. Glioblastoma (GBM) is one of the most common, aggressive, and invasive human brain tumors. There are few reliable mechanism-based therapeutic approaches for GBM patients. The transcriptional repressor RE1 silencing transcriptional factor (REST) regulates the oncogenic properties of a cla...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Marisetty, Anantha L., Singh, Sanjay K., Nguyen, Tran N., Coarfa, Cristian, Liu, Bin, Majumder, Sadhan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Basic and Translational Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5781317/
https://ncbi.nlm.nih.gov/pubmed/28040710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now232
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